RENUVA
REGENERATE YOUTHFUL FULLNESS IN THE FACE, NECK, HANDS, AND BODY FOR NEWTON AND THE BOSTON AREA
Full, healthy fat gives the face its soft contours and youthful shape—but as time passes, this natural volume begins to fade. Aging, weight loss, and everyday environmental stressors can all lead to the breakdown of facial fat, resulting in hollowness, sagging, and a more tired appearance. Renuva from the Boston area’s Dr. Happe Medical Aesthetics offers a groundbreaking solution. Recognized in 2025 as the first and only injectable treatment designed to regenerate your body’s own fat, this anti-aging injectable restores lost volume by activating natural repair processes. The result? A smoother, refreshed look that feels as natural as it appears.
Renuva injections are changing the game in cosmetic treatments—especially when it comes to fat, which can be notoriously difficult to manage. While diet and exercise might help you lose weight, they can’t control where that weight comes from or returns. Genetics decide where your body stores fat, meaning you can’t simply sculpt your ideal contours through lifestyle changes alone. That’s where Renuva stands out: it allows you to guide your body to rebuild volume exactly where it’s needed. So even if you’re slimming down overall, you can still restore softness and youthful fullness in just the right places.
Curious about how Renuva in the Boston area can help you restore youthful volume without surgery? Discover the benefits of this innovative injectable at Dr. Happe Medical Aesthetics in Waban, Newton. Call (617) 597-2600 or submit a contact form to request a consultation.
WHAT SETS RENUVA APART?
*Individual patient results may vary.
You might be asking, “How is Renuva different from fillers?” Most facial fillers on the market today work by adding volume through a gel made from hyaluronic acid—a substance naturally found in the skin. These treatments are highly effective for many patients and can deliver beautifully smooth, youthful results. However, not everyone is satisfied with this approach. Some individuals develop what’s often referred to as “filler fatigue,” where repeated treatments begin to create an unnatural or “overfilled” look. Others are disappointed that although the results appear instantly, they don’t last as long as they’d like.
Renuva offers a completely different strategy for facial rejuvenation. Rather than injecting a synthetic gel to fill volume, Renuva works by activating your body’s natural fat-regeneration process. When injected, Renuva forms a honeycomb-like structure known as an adipose matrix—composed of collagen, growth factors, and other key proteins. This scaffold encourages your body to generate new fat cells in that exact area, gradually restoring fullness with your own living tissue.
Because the results emerge slowly as fat cells develop and integrate with the surrounding tissue, many patients ask, “Does Renuva really work?” The answer is yes—and in a way that feels exceptionally natural. The volume created by Renuva is not artificial. Over time, the scaffold is replaced entirely by your body’s own fat, essentially recreating what was lost to aging, weight changes, or other factors. The result is long-lasting, soft, and undetectably natural rejuvenation that moves and feels like real tissue—because it is.
WHAT ARE THE BENEFITS OF RENUVA?
Renuva is designed to help counteract volume loss in areas that have “native fat.” Some of the most popular treatment areas are the face and neck, including the cheeks, chin, jawline, and temples, as well as next to the mouth and nose—where nasolabial folds form—and on the earlobes. Loss of facial fat can give the midface a hollow or gaunt look, so restoring the fat creates more youthful contours.
Areas of the body ideal for Renuva injections are the hands and décolletage. It can also be used to repair surgical deformations in the breasts, as well as to re-volumize patients who don’t want to risk a surgical breast augmentation. The hands are an especially ideal feature for re- volumizing, since fat loss on the backs of the hands causes veins and tendons to become more prominent.
See below for Renuva before-and-after images.
Before
The patient was treated with Renuva to correct volume loss in her cheeks and submalar area. Individual results may vary.
After
- Two 3cc treatments of Renuva were administered to each side of the patient’s face.
- Each 3cc Renuva treatment was hydrated using 9ml sterile saline (12cc total volume per treatment).
Renuva can also be used to correct contour deficiencies, including the divots associated with cellulite, “hip dips” that develop due to fat distribution, and even irregularities that result from surgery.
FREQUENTLY ASKED QUESTIONS
Renuva can be an excellent option for individuals seeking subtle, natural-looking rejuvenation—especially those who are good candidates for fat grafting but prefer a non-surgical approach. Traditional fat grafting involves liposuction to harvest fat from one part of the body, followed by reinjection into another area. This requires surgery, downtime, and sufficient donor fat, which not every patient has or wants to deal with.
Renuva offers a powerful alternative. As an injectable treatment, Renuva skips the need for fat harvesting altogether, making it less invasive, more accessible, and often more cost-effective. This makes it particularly well-suited for patients who are lean, have limited donor fat, or want to avoid the risks and recovery associated with surgical procedures.
This regenerative injectable is ideal for enhancing small volume deficiencies—such as smoothing out dimples or divots, softening contour irregularities, or gently plumping areas that have lost their youthful fullness over time. Whether you’re looking to refine facial contours, refresh the hands, or subtly improve other areas, Renuva can deliver a naturally fuller, more harmonious appearance—without the need for surgery.
There’s no required downtime after Renuva injections, making this treatment especially convenient for patients with busy schedules. Most people can return to their usual daily activities right away, with minimal disruption. That said, Dr. Holly Happe generally advises avoiding strenuous physical activity—such as vigorous exercise—for about 24 hours after your session. This short window allows the injected area to settle properly and reduces the likelihood of unnecessary swelling or bruising.
Speaking of swelling, patients may notice some puffiness at the injection sites, which is a normal and expected part of the healing process. However, the post-treatment swelling associated with Renuva is typically milder than what patients experience with traditional dermal fillers. Any temporary changes in appearance—such as subtle firmness or volume irregularities—will continue to improve as your body begins generating new fat cells and the treated area integrates naturally over time. Most patients find that the comfort level and quick recovery make Renuva a highly accessible option for gradual, natural-looking rejuvenation.
How long does Renuva take to work? Unlike hyaluronic acid fillers, which provide instant results, Renuva works by stimulating your body to regenerate its own fat—so results develop more gradually. Because this injectable is composed of an adipose-derived extracellular matrix, it acts as a scaffold that signals your body to produce new, living fat cells in the treated area. This biological process takes time, and as a result, the initial appearance won’t reflect the final outcome right away.
Most patients can expect to see approximately 85 percent of their fat volume restoration by the three-month mark after the first treatment. By six months post-injection, the body will have completed the regeneration process, with full results of that session visible. For optimal results, most patients will need multiple treatment sessions. This slow and steady development is one of Renuva’s key advantages, creating exceptionally natural-looking outcomes. Because the new fat cells form precisely where volume was lost—and integrate seamlessly with the surrounding tissue—the results look and feel entirely authentic. There’s no artificial puffiness or displacement, and the new fat will move naturally with your expressions and facial structure.
This gradual transformation also allows for subtle, progressive changes that are less likely to draw attention during the recovery period, making Renuva an ideal option for those seeking discreet rejuvenation. As the fat matures, it continues to enhance the skin’s contours and softness, offering long-lasting improvement that mirrors the effects of a traditional fat transfer—without surgery.
One of the biggest advantages of Renuva is the duration of the results. The gel from fillers breaks down over time, with the added volume lasting anywhere from six months to two years, depending on where it was injected. Fat cells have a much longer lifespan, and the new ones will remain in place, even as you continue to age. Every patient is different, and each cell has its own lifespan, but the typical fat cell lives for about 10 years.
*Individual patient results may vary.
RENUVA VS. SCULPTRA®: WHICH IS THE BETTER OPTION FOR YOU?
Many people also ask about the difference between Renuva and Sculptra®—and the comparison is a good one. Like Renuva, Sculptra® is a biostimulatory injectable, but instead of building fat, it stimulates collagen production over time to gradually enhance volume and skin structure. Radiesse® works similarly, encouraging new collagen formation through a process called neocollagenesis. Since collagen and fat both contribute to facial volume and support, choosing between these options depends on your goals, facial anatomy, and preferences.
WHAT OTHER COSMETIC OPTIONS COMPLEMENT RENUVA IN THE BOSTON AREA?
While Renuva offers a unique approach to restoring lost volume through fat regeneration, it’s just one of many advanced cosmetic treatments available at Dr. Happe Medical Aesthetics in the Boston area. Patients who are better suited to traditional dermal fillers can explore options like the Restylane® and RHA® collections—each made with hyaluronic acid and designed for smooth, customizable results tailored to different areas of the face.
For those concerned with expression-related lines, we also offer wrinkle-relaxing injectables like BOTOX®, Dysport®, and Xeomin®. These neuromodulators soften dynamic wrinkles—such as crow’s feet, frown lines, and forehead creases—by limiting muscle activity beneath the skin for a smoother, more refreshed appearance.
In addition to injectables like Renuva, our skin rejuvenation menu includes treatments like microneedling, chemical peels, and other non-surgical options that improve skin tone, texture, and clarity over time.
The best way to find the right fit—whether you’re comparing Renuva cost, results, or long-term benefits—is to book a personalized consultation. During your visit, you’ll receive one-on-one guidance, see Renuva before-and-after photos,learn more about who would be a good candidate for Renuva, and get answers to any questions you may have. At Dr. Happe Medical Aesthetics, we’re here to connect you with treatments that deliver natural-looking results safely, comfortably,and confidently!
Thinking about Renuva in the Boston area? Let’s talk! Reach out to Dr. Happe Medical Aesthetics to get all your questions answered. Call (617) 597-2600 or fill out a contact form to schedule a consultation.
Environ Skin Care Products
Environ is a professional skin care line recognized around the world for its science-based formulas and results, focusing on the power of Vitamin A and other beneficial ingredients.
Dr. Holly Happe's patients can buy Environ Skin Care online or over the phone, with products shipped directly to their homes.
