Dr. Happe Medical Aesthetics
Newton / Waban, MA

Should BOTOX® Users Give Jeuveau™ a Try?

The newest addition to the category of wrinkle-reducing neuromodulators, Jeuveau (known familiarly as “Newtox”) has been drawing attention, as well as generating questions from people familiar with other, similar brands of muscle-relaxing injections. As explained by Dr. Holly Happe from Dr. Happe Medical Aesthetics in Newton, Jeuveau can be great for long-term former users of BOTOX® who have developed an “immunity” to the popular product.

The four brands of cosmetic neuromodulators available in the United States are BOTOX®, Dysport®, Xeomin®, and Jeuveau. They share key similarities: All contain botulinum toxin type A as an active ingredient and are designed to address wrinkles formed by muscle motion in the face (known as “dynamic wrinkles”). The injections work by temporarily preventing the transmission of messages from the nerves to the muscles, thereby inhibiting contractions. The relaxed muscles allow the face to look more youthful and refreshed, since they stay at rest when certain expressions are made. This keeps skin in the treated areas from being pulled into noticeable folds.

BOTOX® and its fellow neuromodulators are produced from a chemical known as botulinum toxin, which itself is derived from the Clostridium botulinum bacterium found in nature. In addition to its cosmetic applications, the injectable is also used for medical purposes, such as calming spastic muscles and reducing chronic migraine episodes.

BOTOX® is FDA-approved for crow’s feet, elevens, and forehead lines, but also has many off-label uses on bunny lines and other areas. One common misconception about BOTOX® is that it produces an “overdone” or “frozen” appearance. When administered by someone with skill and experience, the effects can be subtle and natural looking. 


Dysport® and Xeomin® are manufactured differently, and their accessory protein content is not the same as their more well-known counterpart. Dysport® is diluted in a unique way, while Xeomin® is a purified version of the drug that does not contain additives and consists of only one ingredient: botulinum toxin.

Unlike the other three neuromodulators available, Jeuveau is only approved for moderate to several glabellar lines (frown lines) between the brows. It serves as a fast-acting, less expensive alternative to the more established BOTOX® brand, and is made solely for aesthetic use.

To find the ideal wrinkle-reducing treatment for your needs, Dr. Happe will assess your complete medical history and facial features. She can help you determine whether it makes sense to switch over to Jeuveau if you’ve already been using another type of neuromodulator. 


Want to learn more about Jeuveau and other neuromodulators? Get started on your treatment plan today by contacting Dr. Happe Medical Aesthetics’ practice. Call 617-597-2600 or request a consultation.

Dr. Happe Medical Aesthetics

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